If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options.

We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide.

Please visit www.jazzpharmaceuticals.com for more information. The Clinical Trial Liaison (CTL) is a field-based scientific expert dedicated to accelerating clinical trial execution. You will build peer-to-peer relationships with Principal Investigators and site staff in Neuroscience and Oncology, providing deep protocol knowledge, addressing site enrollment barriers, and sharing clinical insights.

By enhancing site engagement, you will drive trial performance and support Jazz Pharmaceuticals’ mission to bring innovative medicines to patients.

Essential Functions/Responsibilities Identify and develop peer-to-peer relationships with key opinion leaders (KOLs), Principal investigators, sub-investigators, and healthcare providers within the target therapeutic areas (currently Neuroscience, Oncology and Neuro-oncology) for select Jazz pipeline indications. Serve as the field-based scientific and clinical trial expert and advocate using disease state and pipeline knowledge to engage Principal Investigators (PI’s) and clinical site staff in meaningful discussions regarding the protocol. Lead and drive site engagement strategies and initiatives to improve trial and site operational performance and enhance site relationships by proactively identifying barriers to patient screening, enrollment, and retention at clinical sites.

Collaborate with key cross-functional stakeholders to develop and execute territory plans in alignment with site engagement objectives, plans and deliverables while ensuring close partnership internally and with CRO partners to share insight and ensure alignment with site engagement activities without duplicating efforts. Identify and communicate key clinical and research issues and insights from clinical research sites and healthcare providers to clinical study teams; providing recommendations and creative solutions, as appropriate. Participate in clinical study education for healthcare professionals (HCPs) in communities around clinical trial sites.

Support sites through on-site presentations at healthcare institutions at conferences, in local healthcare institutions and surrounding communities. Provide scientific support as needed in support of site patient and site engagement deliverables including but not limited to site and patient study specific material development. Document and forward reports of adverse events and product complaints according to Jazz’s policy to ensure safe and effective use of Jazz Pharmaceuticals' products.

Adhere to the relevant national and local Codes of Practice. Required Knowledge, Skills, and Abilities Strategic mindset with the ability to research and critically analyze and communicate complex scientific and medical information and data and integrate this into site engagement plans and activities. Clear and concise communication and presentation skills.

Excellent planning and organization skills, with high-level attention to detail and accuracy. Demonstrated skills in inter-personal relationship building, networking, collaboration, and teamwork, specifically with HCPs and other leading professionals in the scientific and medical community. Highly self-motivated and ability to work autonomously.

Ability to learn quickly, be flexible and results-focused in a rapidly changing environment. Requires the ability to influence without authority or gain acceptance/consensus from others in sensitive situations, without damage to the relationship. Strong capabilities working with digital platforms and tools are required.

Knowledge of target geography(s), healthcare environment(s) and external experts in academia and medical community. Well established network and demonstrated ability to develop trust and relationships with opinion leaders, PIs, clinical trial networks, and site research staff in disease states of interest. Strong understanding of clinical trial methodology, GCP, and the overall drug development process and its regulatory requirements; understanding of regulatory and legal requirements for field-based personnel interacting with HCPs.

Comfortable working outside of “normal” work hours, in order to meet business demands. Excellent command of written and spoken English. Required/Preferred Education and Licenses Advanced degree (PharmD, MD, PhD or equivalent) with a minimum of 3 years of experience in oncology and/or neuroscience medicine is required, or License (RN, NP, CNP, PA or equivalent) with a minimum of a Master’s Degree (or equivalent) and a minimum of 5 years’ experience in oncology and/or neuroscience medicine is required.

A minimum of 2 years of experience as a Medical Scientific Liaison (MSL), Clinical Scientist, ,Clinical Trial Liaison (CTL), or comparable field-based industry or clinical role is required. Strong track record of experience and demonstrated success in target therapy areas and indications (e.g., targeted therapies for solid tumors, epilepsy, etc.) is strongly preferred. This is a field position, and applicants must be willing to travel up to 60% of time.

Valid driver’s license and live in proximity of a major airport. LI-DM1 LI-Remote Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc.

is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $121,600.00 - $182,400.00 Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy.

Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package.

The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html .

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options.

We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide.

Please visit www.jazzpharmaceuticals.com for more information.

Brief Description: The Senior Director, Head of Global Study Management is a key leadership role within Clinical Operations at Jazz Pharmaceuticals. Reporting directly to the Executive Director, Head of Clinical Operations, the successful candidate will sit on the Clinical Operations Leadership Team and play an integral role in shaping strategic vision, operational execution, and organizational capability across Global Study Management and Clinical Operations more broadly at Jazz. This role requires a Clinical Operations expert with a strong track record in clinical trial delivery, strategic functional leadership, and robust financial acumen. The ideal candidate will combine deep technical expertise in clinical study execution with a broad enterprise perspective, leading global teams to deliver clinical development programs efficiently, with high quality, compliance and innovation.

Essential Functions/Responsibilities: Strategic Leadership & Organizational Vision Define and articulate the strategic vision and long-term direction for the Global Study Management function, aligned with GCDO and broader R&D strategic goals. Serve as an active and impactful member of the Clinical Operations Leadership Team, contributing to overall department governance, resource planning, and operational excellence. Foster a high-performance, inclusive culture across the Global Study Management organization, embedding accountability, continuous learning, and operational agility. Study Delivery & Operational Oversight Partner with Program Leadership and Strategic Trial Optimization in the operational planning and execution of the Jazz Pharmaceuticals’ clinical trial portfolio. Ensure robust operational oversight of trial execution against established key performance indicators (KPIs), timelines, quality standards, and budget targets. Provide direction and escalation resolution for complex operational challenges, ensuring portfolio delivery aligns with overarching clinical development plans. Line Management & Capability Building Provide direct leadership, mentoring, and professional development to Global Study Management leaders, enabling succession planning and top-talent retention. Build and scale functional capabilities, ensuring Global Study Management teams have the competencies, tools, and resources required to plan and execute complex trials. Promote global team alignment and flexible resourcing models capable of operating seamlessly across international time zones and geographic regions. Enterprise Partnering & Cross-Functional Alignment Build effective, collaborative partnerships across Global Clinical Development Operations and R&D stakeholders (including Clinical Development, Regulatory Affairs, Biostatistics, Quality Assurance, and Global Supply Chain). Maintain a strong enterprise perspective, balancing functional excellence with broader strategic and business objectives. Financial Oversight & Budgetary Control Drive financial stewardship and budgetary control across the Global Study Management function. Oversee financial planning, trial forecasting, resource allocation, and contribute to cost optimization initiatives across all global clinical trials. Quality, Compliance & Inspection Readiness Ensure all global study management activities adhere strictly to ICH GCP guidelines, applicable global regulatory requirements and company SOPs. Drive a culture of continuous audit and inspection readiness across all trial management activities. Required Knowledge, Skills, and Abilities Proven Track Record in Clinical Trial Delivery: Demonstrated track record of leading complex, global Phase I–IV clinical study execution across multiple therapeutic areas (Required). Deep experience of Oncology, Rare Disease or Neuroscience (preferred).

Functional Leadership Experience: Extensive leadership experience within a global study management or clinical operations organization in the biopharmaceutical industry or Clinical Research Organization (CRO).

Strategic Capability: A demonstrated track record of strategic functional leadership, organizational design, and departmental vision setting (Desirable).

Technical & Enterprise Balance: Demonstrated ability to manage complex technical details within the function while consistently maintaining a strategic enterprise perspective.

Strategic Partnering: Skilled at collaborating with Clinical Development and medical experts to translate scientific concepts into operationally viable study designs and execution plans.

Financial Acumen: Adept at constructing, analyzing, and optimizing functional workforce budgets in support of short- and mid-term planning activities Self-Starter & Results-Driven: A highly motivated, resilient self-starter with a proactive approach to solving complex operational challenges.

Global Mindset & Flexibility: Proven capability to operate effectively across a matrixed global environment, requiring time zone flexibility to support multi-regional teams and study sites.

High-Performance Culture Builder: Demonstrated ability to inspire, motivate, and embed high-performance practices within a growing study management organization.

Communication & Influencing: Superior communication, negotiation, and stakeholder management skills, capable of influencing decisions at executive leadership levels . Required/Preferred Education and Licenses Bachelor’s degree in Life Sciences, Allied Health, or related field required; advanced degree (MS, PharmD, PhD, or MBA) strongly preferred. Significant biopharmaceutical industry experience in clinical trial operations, with significant senior leadership responsibility in Global Study management. Direct line management (required), including leadership of people managers (preferred) Closing date for applications is November 6 Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $236,000.00 - $354,000.00 Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html .

If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options.

We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide.

Please visit www.jazzpharmaceuticals.com for more information. Senior Medical Director, Solid Tumor Oncology Position Summary The Senior Medical Director, Solid Tumor Oncology , is a senior clinical leader responsible for shaping and executing the medical and clinical strategy for solid tumor programs across the drug development lifecycle. This role provides deep scientific and medical leadership, drives high‑quality evidence generation, partners cross‑functionally to advance pipeline assets, and represents the organization to external stakeholders, including regulatory agencies, investigators, and key opinion leaders.

The Senior Medical Director is accountable for ensuring robust clinical development plans, patient‑centric trial designs, and scientifically rigorous decision‑making aligned with the company’s oncology strategy. Key Responsibilities Clinical & Medical Leadership Provide strategic medical oversight for solid tumor oncology programs from early development through registration and post‑approval. Serve as the medical authority for assigned assets, ensuring scientific integrity, patient safety, and regulatory compliance.

Guide clinical trial design, endpoint selection, biomarker strategy, and translational integration. Oversee medical monitoring and contribute to safety governance committees, including SMCs and DMCs as needed. Development Strategy & Execution Lead the development and execution of integrated clinical development plans aligned with unmet medical needs and competitive landscape.

Collaborate with Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, and Translational Medicine to drive timely and high‑quality trial delivery. Contribute to portfolio strategy, asset prioritization, and lifecycle management decisions. Regulatory & External Engagement Act as a key medical contributor in regulatory interactions with global health authorities (e.g., FDA, EMA).

Support preparation and review of regulatory documents, including protocols, CSRs, IBs, IND/CTA submissions, and briefing packages. Build and maintain strong relationships with investigators, academic collaborators, and external experts. Medical Affairs & Scientific Communication Partner with Medical Affairs to ensure seamless transition from development to launch and post‑marketing activities.

Contribute to publication strategy, abstract development, congress presentations, and scientific exchange. Serve as a credible scientific spokesperson for solid tumor programs, internally and externally. Leadership & Talent Development Provide mentorship and leadership to medical directors and physicians within the oncology organization.

Foster a culture of scientific excellence, collaboration, accountability, and patient focus. Influence cross‑functional teams through thought leadership rather than authority alone.

Qualifications Education & Training MD or MD/PhD required; board certification in Oncology, Hematology‑Oncology, or a related specialty required. Advanced clinical training and experience in solid tumor oncology required.

Experience 10 years of clinical and/or pharmaceutical industry experience in oncology, with significant solid tumor focus ( thoracic oncology experience preferred ). Demonstrated leadership in global clinical development and late‑phase programs. Proven experience with regulatory interactions and contribution to successful filings.

Track record of strategic leadership across complex, matrixed organizations.

Skills & Competencies Strong strategic thinking combined with operational execution skills. Excellent communication, influencing, and stakeholder‑management capabilities. High ethical standards, sound medical judgment, and strong patient‑centric mindset.

Preferred Attributes Experience leading registrational or practice‑changing Thoracic oncology studies . Familiarity with biomarker‑driven development and precision oncology approaches. Comfort operating in fast‑paced, evolving pipeline environments.

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLY Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive.

For this role, the full and complete base pay range is: $308,000.00 - $462,000.00 Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions.

This range will be reviewed on a regular basis. At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html .